An atlas of Wnt activity during embryogenesis in Xenopus tropicalis.

An atlas of Wnt activity during embryogenesis in Xenopus tropicalis.

Blog Article

Wnt proteins form a family of highly conserved secreted molecules that Washer Hose are critical mediators of cell-cell signaling during embryogenesis.Partial data on Wnt activity in different tissues and at different stages have been reported in frog embryos.Our objective here is to provide a coherent and detailed description of Wnt activity throughout embryo development.Using a transgenic Xenopus tropicalis line carrying a Wnt-responsive reporter sequence, we depict the spatial and temporal dynamics of canonical Wnt activity during embryogenesis.We provide a comprehensive series of in situ hybridization in whole-mount embryos and in cross-sections, from gastrula to tadpole stages, with special focus on neural tube, retina and neural crest cell development.

This collection of patterns will thus constitute a valuable resource for developmental biologists to picture the dynamics of DC Motor Set Wnt activity during development.